6N3F
Structure of HIV Tat-specific factor 1 U2AF Homology Motif bound to SF3b1 ULM5
Summary for 6N3F
Entry DOI | 10.2210/pdb6n3f/pdb |
Descriptor | HIV Tat-specific factor 1, SF3b1 U2AF ligand motif, DI(HYDROXYETHYL)ETHER, ... (5 entities in total) |
Functional Keywords | hiv tat-specific factor 1, tat-sf1, rna splicing factor, u2af homology motif, uhm, rna binding protein, u2af ligand motif, ulm, protein-peptide complex, pre-mrna splicing factor, sf3b1, peptide binding protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 23196.99 |
Authors | Leach, J.R.,Jenkins, J.L.,Kielkopf, C.L. (deposition date: 2018-11-15, release date: 2019-01-02, Last modification date: 2024-03-13) |
Primary citation | Loerch, S.,Leach, J.R.,Horner, S.W.,Maji, D.,Jenkins, J.L.,Pulvino, M.J.,Kielkopf, C.L. The pre-mRNA splicing and transcription factor Tat-SF1 is a functional partner of the spliceosome SF3b1 subunit via a U2AF homology motif interface. J. Biol. Chem., 294:2892-2902, 2019 Cited by PubMed: 30567737DOI: 10.1074/jbc.RA118.006764 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.099 Å) |
Structure validation
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