6N3F

Structure of HIV Tat-specific factor 1 U2AF Homology Motif bound to SF3b1 ULM5

6N3F の概要

• エントリーDOI: 10.2210/pdb6n3f/pdb
• 分子名称: HIV Tat-specific factor 1, SF3b1 U2AF ligand motif, DI(HYDROXYETHYL)ETHER, ... (5 entities in total)
• 機能のキーワード: hiv tat-specific factor 1, tat-sf1, rna splicing factor, u2af homology motif, uhm, rna binding protein, u2af ligand motif, ulm, protein-peptide complex, pre-mrna splicing factor, sf3b1, peptide binding protein
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 23196.99

構造登録者

Leach, J.R.,Jenkins, J.L.,Kielkopf, C.L. (登録日: 2018-11-15, 公開日: 2019-01-02, 最終更新日: 2024-03-13)

• 主引用文献: Loerch, S.,Leach, J.R.,Horner, S.W.,Maji, D.,Jenkins, J.L.,Pulvino, M.J.,Kielkopf, C.L.; The pre-mRNA splicing and transcription factor Tat-SF1 is a functional partner of the spliceosome SF3b1 subunit via a U2AF homology motif interface.; J. Biol. Chem., 294:2892-2902, 2019; PubMed: 30567737; DOI: 10.1074/jbc.RA118.006764

実験手法

X-RAY DIFFRACTION (2.099 Å)