X-ray crystal structure of Bacillus subtilis ribonucleotide reductase NrdE alpha subunit with TTP and ADP

Summary for 6MV9

DescriptorRibonucleoside-diphosphate reductase, THYMIDINE-5'-TRIPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, ... (4 entities in total)
Functional Keywordsribonucleotide reductase, allostery, nucleotide metabolism, datp, atp, oxidoreductase
Biological sourceBacillus subtilis
Total number of polymer chains2
Total molecular weight163450.29
Thomas, W.C.,Brooks, F.P.,Bacik, J.P.,Ando, N. (deposition date: 2018-10-24, release date: 2019-06-19, Last modification date: 2019-06-26)
Primary citation
Thomas, W.C.,Brooks 3rd, F.P.,Burnim, A.A.,Bacik, J.P.,Stubbe, J.,Kaelber, J.T.,Chen, J.Z.,Ando, N.
Convergent allostery in ribonucleotide reductase.
Nat Commun, 10:2653-2653, 2019
PubMed: 31201319 (PDB entries with the same primary citation)
DOI: 10.1038/s41467-019-10568-4
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.23850 2.5% 0.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report