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6MUB

Anti-HIV-1 Fab 2G12 + Man5 re-refinement

Replaces:  1ZLU
Summary for 6MUB
Entry DOI10.2210/pdb6mub/pdb
DescriptorFab 2G12, light chain, Fab 2G12, heavy chain, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose, ... (4 entities in total)
Functional Keywordsantibody, carbohydrate, hiv-1, immune system
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains4
Total formula weight96221.16
Authors
Wilson, I.A.,Calarese, D.A.,Stanfield, R.L. (deposition date: 2018-10-22, release date: 2018-10-31, Last modification date: 2023-10-11)
Primary citationCalarese, D.A.,Lee, H.K.,Huang, C.Y.,Best, M.D.,Astronomo, R.D.,Stanfield, R.L.,Katinger, H.,Burton, D.R.,Wong, C.H.,Wilson, I.A.
Dissection of the carbohydrate specificity of the broadly neutralizing anti-HIV-1 antibody 2G12.
Proc.Natl.Acad.Sci.USA, 102:13372-13377, 2005
Cited by
PubMed: 16174734
DOI: 10.1073/pnas.0505763102
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.503 Å)
Structure validation

218500

数据于2024-04-17公开中

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