6MMU

Triheteromeric NMDA receptor GluN1/GluN2A/GluN2A* in the '2-Knuckle-Asymmetric' conformation, in complex with glycine and glutamate, in the presence of 1 micromolar zinc chloride, and at pH 7.4

6MMU の概要

• エントリーDOI: 10.2210/pdb6mmu/pdb
• EMDBエントリー: 9147 9148 9149 9150 9151 9152 9153 9154 9155 9156 9157 9158 9159 9160 9161 9162 9163 9164 9165
• 分子名称: Glutamate receptor ionotropic, NMDA 1, Glutamate receptor ionotropic, NMDA 2A, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• 機能のキーワード: ligand-gated ion channel, nmda receptor, ionotropic glutamate receptors, membrane protein, transport protein
• 由来する生物種: Rattus norvegicus (Rat); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 384139.05

構造登録者

Jalali-Yazdi, F.,Chowdhury, S.,Yoshioka, C.,Gouaux, E. (登録日: 2018-10-01, 公開日: 2018-11-28, 最終更新日: 2020-07-29)

• 主引用文献: Jalali-Yazdi, F.,Chowdhury, S.,Yoshioka, C.,Gouaux, E.; Mechanisms for Zinc and Proton Inhibition of the GluN1/GluN2A NMDA Receptor.; Cell, 175:1520-1532.e15, 2018; PubMed: 30500536; DOI: 10.1016/j.cell.2018.10.043

実験手法

ELECTRON MICROSCOPY (5.3 Å)