6MKW

Crystal structure of the periplasmic Lysine-, Arginine-, Ornithine-binding protein (LAO) D11A mutant from Salmonella typhimurium complexed with histidine

Summary for 6MKW

• Entry DOI: 10.2210/pdb6mkw/pdb
• Related: 6MKU 6MKX 6ML0 6ML9 6MLA 6MLE 6MLG 6MLI 6MLJ 6MLN 6MLO 6MLP 6MLV
• Descriptor: Lysine/arginine/ornithine transport protein, HISTIDINE, GLYCEROL, ... (4 entities in total)
• Functional Keywords: periplasmic binding protein, lao, thermodynamics, protein ligand complex, protein binding
• Biological source: Salmonella typhimurium (strain 14028s / SGSC 2262)
• Total number of polymer chains: 1
• Total formula weight: 26283.57

Authors

Romero-Romero, S.,Vergara, R.,Espinoza-Perez, G.,Rodriguez-Romero, A. (deposition date: 2018-09-26, release date: 2019-08-07, Last modification date: 2023-10-11)

• Primary citation: Vergara, R.,Romero-Romero, S.,Velazquez-Lopez, I.,Espinoza-Perez, G.,Rodriguez-Hernandez, A.,Pulido, N.O.,Sosa-Peinado, A.,Rodriguez-Romero, A.,Fernandez-Velasco, D.A.; The interplay of protein-ligand and water-mediated interactions shape affinity and selectivity in the LAO binding protein.; Febs J., 287:763-782, 2020; PubMed: 31348608; DOI: 10.1111/febs.15019

Experimental method

X-RAY DIFFRACTION (2.32 Å)