6MK4
Solution NMR structure of spider toxin analogue [E17K]ProTx-II
Summary for 6MK4
| Entry DOI | 10.2210/pdb6mk4/pdb |
| NMR Information | BMRB: 30521 |
| Descriptor | Beta/omega-theraphotoxin-Tp2a (1 entity in total) |
| Functional Keywords | protx-ii analogue, spider toxin, peptide-membrane interactions, voltage-sensitive sodium channels, toxin |
| Biological source | Thrixopelma pruriens (Peruvian green velvet tarantula) |
| Total number of polymer chains | 1 |
| Total formula weight | 3839.75 |
| Authors | Schroeder, C.I. (deposition date: 2018-09-25, release date: 2018-12-19, Last modification date: 2023-06-14) |
| Primary citation | Lawrence, N.,Wu, B.,Ligutti, J.,Cheneval, O.,Agwa, A.J.,Benfield, A.H.,Biswas, K.,Craik, D.J.,Miranda, L.P.,Henriques, S.T.,Schroeder, C.I. Peptide-Membrane Interactions Affect the Inhibitory Potency and Selectivity of Spider Toxins ProTx-II and GpTx-1. ACS Chem. Biol., 14:118-130, 2019 Cited by PubMed: 30507158DOI: 10.1021/acschembio.8b00989 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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