6MJY
M. thermoresistible GuaB2 delta-CBS in complex with 6Cl-IMP
Summary for 6MJY
Entry DOI | 10.2210/pdb6mjy/pdb |
Descriptor | Inosine-5'-monophosphate dehydrogenase, 6-CHLOROPURINE RIBOSIDE, 5'-MONOPHOSPHATE (3 entities in total) |
Functional Keywords | complex, fragment, impdh, oxidoreductase, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor |
Biological source | Mycobacterium thermoresistibile More |
Total number of polymer chains | 1 |
Total formula weight | 40222.14 |
Authors | Ascher, D.B.,Pacitto, A.,Blundell, T.L. (deposition date: 2018-09-23, release date: 2019-09-25, Last modification date: 2023-10-11) |
Primary citation | Trapero, A.,Pacitto, A.,Chan, D.S.,Abell, C.,Blundell, T.L.,Ascher, D.B.,Coyne, A.G. Covalent inactivation of Mycobacterium thermoresistibile inosine-5'-monophosphate dehydrogenase (IMPDH). Bioorg.Med.Chem.Lett., 30:126792-126792, 2020 Cited by PubMed: 31757668DOI: 10.1016/j.bmcl.2019.126792 PDB entries with the same primary citation |
Experimental method |
Structure validation
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