6MJL

Crystal structure of ChREBP NLS peptide bound to importin alpha.

Summary for 6MJL

• Entry DOI: 10.2210/pdb6mjl/pdb
• Descriptor: Importin subunit alpha-1, ChREBP Peptide ASN-TYR-TRP-LYS-ARG-ARG-ILE-GLU-VAL (3 entities in total)
• Functional Keywords: chrebp, importin alpha, transcription, transcription-peptide complex, transcription/peptide
• Biological source: Mus musculus (Mouse); More
• Total number of polymer chains: 2
• Total formula weight: 47410.30

Authors

Jung, H.,Uyeda, K. (deposition date: 2018-09-21, release date: 2019-09-25, Last modification date: 2024-03-13)

• Primary citation: Jung, H.,Takeshima, T.,Nakagawa, T.,MacMillan, K.S.,Wynn, R.M.,Wang, H.,Sakiyama, H.,Wei, S.,Li, Y.,Bruick, R.K.,Posner, B.A.,De Brabander, J.K.,Uyeda, K.; The structure of importin alpha and the nuclear localization peptide of ChREBP, and small compound inhibitors of ChREBP-importin alpha interactions.; Biochem.J., 477:3253-3269, 2020; PubMed: 32776146; DOI: 10.1042/BCJ20200520

Experimental method

X-RAY DIFFRACTION (2.5 Å)