6MJA

Crystal structure of the mCD1d/xxo (JJ294) /iNKTCR ternary complex

6MJA の概要

• エントリーDOI: 10.2210/pdb6mja/pdb
• 分子名称: T cell receptor alpha variable 11,T cell receptor alpha variable 11,T cell receptor alpha joining 18,Human nkt tcr alpha chain, CHIMERIC PROTEIN, N-[(2S,3S,4R)-3,4-dihydroxy-1-({4-O-[(4-methylphenyl)methyl]-alpha-D-galactopyranosyl}oxy)octadecan-2-yl]hexacosanamide, Beta-chain,T cell receptor chain,T cell receptor beta constant 2, CHIMERIC PROTEIN, ... (11 entities in total)
• 機能のキーワード: mhc-fold, ig-fold, glycolipid antigen presentation, t cell receptor, immune system
• 由来する生物種: Mus musculus (Mouse); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 97038.66

構造登録者

Zajonc, D.M.,Bitra, A.,Janssens, J. (登録日: 2018-09-20, 公開日: 2019-01-09, 最終更新日: 2023-10-11)

• 主引用文献: Janssens, J.,Bitra, A.,Wang, J.,Decruy, T.,Venken, K.,van der Eycken, J.,Elewaut, D.,Zajonc, D.M.,van Calenbergh, S.; 4"-O-Alkylated alpha-Galactosylceramide Analogues as iNKT-Cell Antigens: Synthetic, Biological, and Structural Studies.; ChemMedChem, 14:147-168, 2019; PubMed: 30556652; DOI: 10.1002/cmdc.201800649

実験手法

X-RAY DIFFRACTION (2.35 Å)