6MGE

Structure of human 4-1BBL

6MGE の概要

• エントリーDOI: 10.2210/pdb6mge/pdb
• 分子名称: Tumor necrosis factor ligand superfamily member 9, PHOSPHATE ION, GLYCEROL, ... (4 entities in total)
• 機能のキーワード: signaling, tnf ligand, trimer, 4-1bbl, cd137l, immune system
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 66380.22

構造登録者

Kimberlin, C.R.,Chin, S.M.,Roe-Zurz, Z.,Xu, A.,Yang, Y. (登録日: 2018-09-13, 公開日: 2018-11-21, 最終更新日: 2023-10-11)

• 主引用文献: Chin, S.M.,Kimberlin, C.R.,Roe-Zurz, Z.,Zhang, P.,Xu, A.,Liao-Chan, S.,Sen, D.,Nager, A.R.,Oakdale, N.S.,Brown, C.,Wang, F.,Yang, Y.,Lindquist, K.,Yeung, Y.A.,Salek-Ardakani, S.,Chaparro-Riggers, J.; Structure of the 4-1BB/4-1BBL complex and distinct binding and functional properties of utomilumab and urelumab.; Nat Commun, 9:4679-4679, 2018; PubMed: 30410017; DOI: 10.1038/s41467-018-07136-7

実験手法

X-RAY DIFFRACTION (2.95 Å)