6MG7

Crystal structure of the RV144 C1-C2 specific antibody CH54 Fab in complex with HIV-1 CLADE A/E GP120 and M48U1

6MG7 の概要

• エントリーDOI: 10.2210/pdb6mg7/pdb
• 関連するBIRD辞書のPRD_ID: PRD_001094
• 分子名称: clade A/E 93TH057 HIV-1 gp120 core, M48U1 CD4 mimetic peptide, CH54 Fab heavy chain, ... (5 entities in total)
• 機能のキーワード: anti-hiv-1 env antibody ch54, cd4i antibody, adcc, hiv-1 env, immune system, rv144 vaccine trial, clade a/e 93th057, viral protein-immune system complex, viral protein/immune system
• 由来する生物種: Human immunodeficiency virus 1; 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 94286.22

構造登録者

Van, V.,Tolbert, W.D.,Pazgier, M. (登録日: 2018-09-13, 公開日: 2019-09-25, 最終更新日: 2023-11-15)

• 主引用文献: Tolbert, W.D.,Van, V.,Sherburn, R.,Tuyishime, M.,Yan, F.,Nguyen, D.N.,Stanfield-Oakley, S.,Easterhoff, D.,Bonsignori, M.,Haynes, B.F.,Moody, M.A.,Ray, K.,Ferrari, G.,Lewis, G.K.,Pazgier, M.; Recognition Patterns of the C1/C2 Epitopes Involved in Fc-Mediated Response in HIV-1 Natural Infection and the RV114 Vaccine Trial.; Mbio, 11:-, 2020; PubMed: 32605979; DOI: 10.1128/mBio.00208-20

実験手法

X-RAY DIFFRACTION (2.91 Å)