6MG4
Structure of full-length human lambda-6A light chain JTO
Summary for 6MG4
Entry DOI | 10.2210/pdb6mg4/pdb |
Descriptor | JTO light chain (2 entities in total) |
Functional Keywords | light chain, amyloidosis, immune system |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 46859.64 |
Authors | Morgan, G.J.,Yan, N.L.,Mortenson, D.E.,Stanfield, R.L.,Wilson, I.A.,Kelly, J.W. (deposition date: 2018-09-12, release date: 2019-04-10, Last modification date: 2023-10-11) |
Primary citation | Morgan, G.J.,Yan, N.L.,Mortenson, D.E.,Rennella, E.,Blundon, J.M.,Gwin, R.M.,Lin, C.Y.,Stanfield, R.L.,Brown, S.J.,Rosen, H.,Spicer, T.P.,Fernandez-Vega, V.,Merlini, G.,Kay, L.E.,Wilson, I.A.,Kelly, J.W. Stabilization of amyloidogenic immunoglobulin light chains by small molecules. Proc.Natl.Acad.Sci.USA, 116:8360-8369, 2019 Cited by PubMed: 30971495DOI: 10.1073/pnas.1817567116 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.75 Å) |
Structure validation
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