6MFQ

Crystal structure of a PMS2 variant

Summary for 6MFQ

Entry DOI	10.2210/pdb6mfq/pdb
Descriptor	Mismatch repair endonuclease PMS2 (2 entities in total)
Functional Keywords	mismatch repair, variant of uncertain significance, atpase domain, hydrolase, dna repair enzyme
Biological source	Homo sapiens (Human)
Total number of polymer chains	2
Total formula weight	81997.53
Authors	D'Arcy, B.M.,Prakash, A. (deposition date: 2018-09-11, release date: 2019-02-06, Last modification date: 2023-10-11)
Primary citation	D'Arcy, B.M.,Blount, J.,Prakash, A. Biochemical and structural characterization of two variants of uncertain significance in the PMS2 gene. Hum. Mutat., 40:458-471, 2019 Cited by PubMed: 30653781 DOI: 10.1002/humu.23708 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.6 Å)

Structure validation