6MFE

Schistosoma mansoni (Blood Fluke) Sulfotransferase/CIDD-0000773 (Compound 11g) Complex

6MFE の概要

• エントリーDOI: 10.2210/pdb6mfe/pdb
• 分子名称: Sulfotransferase oxamniquine resistance protein, ADENOSINE-3'-5'-DIPHOSPHATE, (2-nitro-4-{[(3S)-1-{[4-(trifluoromethoxy)phenyl]methyl}pyrrolidin-3-yl]amino}phenyl)methanol, ... (4 entities in total)
• 機能のキーワード: sulfotransferase, parasite, drug resistance, transferase
• 由来する生物種: Schistosoma mansoni (Blood fluke)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 30919.12

構造登録者

Taylor, A.B. (登録日: 2018-09-10, 公開日: 2018-10-03, 最終更新日: 2023-10-11)

• 主引用文献: Rugel, A.,Tarpley, R.S.,Lopez, A.,Menard, T.,Guzman, M.A.,Taylor, A.B.,Cao, X.,Kovalskyy, D.,Chevalier, F.D.,Anderson, T.J.C.,Hart, P.J.,LoVerde, P.T.,McHardy, S.F.; Design, Synthesis, and Characterization of Novel Small Molecules as Broad Range Antischistosomal Agents.; ACS Med Chem Lett, 9:967-973, 2018; PubMed: 30344901; DOI: 10.1021/acsmedchemlett.8b00257

実験手法

X-RAY DIFFRACTION (1.444 Å)