6MCW

Crystal structure of the P450 domain of the CYP51-ferredoxin fusion protein from Methylococcus capsulatus, complex with the detergent Anapoe-X-114

6MCW の概要

• エントリーDOI: 10.2210/pdb6mcw/pdb
• 分子名称: Cytochrome P450 51, 23-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]-3,6,9,12,15,18,21-heptaoxatricosan-1-ol, PROTOPORPHYRIN IX CONTAINING FE, ... (4 entities in total)
• 機能のキーワード: cytochrome p450 fold, cyp51, heme, sterol biosynthesis, oxidoreductase
• 由来する生物種: Methylococcus capsulatus (strain ATCC 33009 / NCIMB 11132 / Bath)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 63659.10

構造登録者

Hargrove, T.,Wawrzak, Z.,Lamb, D.C.,Lepesheva, G.I. (登録日: 2018-09-02, 公開日: 2019-07-10, 最終更新日: 2023-10-11)

• 主引用文献: Lamb, D.C.,Hargrove, T.Y.,Zhao, B.,Wawrzak, Z.,Goldstone, J.V.,Nes, W.D.,Kelly, S.L.,Waterman, M.R.,Stegeman, J.J.,Lepesheva, G.I.; Concerning P450 evolution: Structural Analyses Support Bacterial Origin of Sterol 14 alpha-Demethylases.; Mol.Biol.Evol., 2020; PubMed: 33031537; DOI: 10.1093/molbev/msaa260

実験手法

X-RAY DIFFRACTION (2.4 Å)