6MBT

Crystal structure of wild-type KRAS bound to GDP and Mg (Space group C2)

Summary for 6MBT

• Entry DOI: 10.2210/pdb6mbt/pdb
• Descriptor: GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... (4 entities in total)
• Functional Keywords: kras, ras, mg, k-ras, small gtpase, guanine nucleotide, oncoprotein, gdp
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 39592.63

Authors

Dharmaiah, S.,Tran, T.H.,Yan, W.,Simanshu, D.K. (deposition date: 2018-08-30, release date: 2019-07-31, Last modification date: 2023-10-11)

• Primary citation: Dharmaiah, S.,Tran, T.H.,Messing, S.,Agamasu, C.,Gillette, W.K.,Yan, W.,Waybright, T.,Alexander, P.,Esposito, D.,Nissley, D.V.,McCormick, F.,Stephen, A.G.,Simanshu, D.K.; Structures of N-terminally processed KRAS provide insight into the role of N-acetylation.; Sci Rep, 9:10512-10512, 2019; PubMed: 31324887; DOI: 10.1038/s41598-019-46846-w

Experimental method

X-RAY DIFFRACTION (1.45 Å)