6MBB
Human Bfl-1 in complex with the designed peptide dF1
Summary for 6MBB
Entry DOI | 10.2210/pdb6mbb/pdb |
Descriptor | Bcl-2-related protein A1, dF1 (3 entities in total) |
Functional Keywords | anti-apoptotic bcl-2, inhibitor, design, apoptosis |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 19966.75 |
Authors | Jenson, J.M.,Keating, A.E. (deposition date: 2018-08-29, release date: 2019-03-06, Last modification date: 2020-01-01) |
Primary citation | Frappier, V.,Jenson, J.M.,Zhou, J.,Grigoryan, G.,Keating, A.E. Tertiary Structural Motif Sequence Statistics Enable Facile Prediction and Design of Peptides that Bind Anti-apoptotic Bfl-1 and Mcl-1. Structure, 27:606-617.e5, 2019 Cited by PubMed: 30773399DOI: 10.1016/j.str.2019.01.008 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.59 Å) |
Structure validation
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