6M9W

Structure of Mg-free KRAS4b (2-169) bound to GDP with the switch-I in fully open conformation

Summary for 6M9W

Entry DOI	10.2210/pdb6m9w/pdb
Descriptor	GTPase KRas, GUANOSINE-5'-DIPHOSPHATE (3 entities in total)
Functional Keywords	kras, ras, mg, k-ras-4b, small gtpase, guanine nucleotide, oncoprotein
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	19697.87
Authors	Dharmaiah, S.,Tran, T.H.,Yan, W.,Simanshu, D.K. (deposition date: 2018-08-24, release date: 2019-07-31, Last modification date: 2023-10-11)
Primary citation	Dharmaiah, S.,Tran, T.H.,Messing, S.,Agamasu, C.,Gillette, W.K.,Yan, W.,Waybright, T.,Alexander, P.,Esposito, D.,Nissley, D.V.,McCormick, F.,Stephen, A.G.,Simanshu, D.K. Structures of N-terminally processed KRAS provide insight into the role of N-acetylation. Sci Rep, 9:10512-10512, 2019 Cited by PubMed: 31324887 DOI: 10.1038/s41598-019-46846-w PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.5 Å)

Structure validation