6M82

Crystal structure of TylM1 Y14paF bound to SAH and dTDP-phenol

6M82 の概要

• エントリーDOI: 10.2210/pdb6m82/pdb
• 分子名称: dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose N,N-dimethyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, 5'-O-[(S)-hydroxy{[(S)-hydroxy(phenoxy)phosphoryl]oxy}phosphoryl]thymidine, ... (5 entities in total)
• 機能のキーワード: tylm1, n-methyltransferase, transferase
• 由来する生物種: Streptomyces fradiae
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 29461.66

構造登録者

Fick, R.J.,McDole, B.G.,Trievel, R.C. (登録日: 2018-08-21, 公開日: 2019-03-13, 最終更新日: 2019-11-27)

• 主引用文献: Fick, R.J.,Horowitz, S.,McDole, B.G.,Clay, M.C.,Mehl, R.A.,Al-Hashimi, H.M.,Scheiner, S.,Trievel, R.C.; Structural and Functional Characterization of Sulfonium Carbon-Oxygen Hydrogen Bonding in the Deoxyamino Sugar Methyltransferase TylM1.; Biochemistry, 58:2152-2159, 2019; PubMed: 30810306; DOI: 10.1021/acs.biochem.8b01141

実験手法

X-RAY DIFFRACTION (1.3971 Å)