6M7U
Human DNA polymerase eta in a non-productive ternary complex with Mg2+ and dTMPNPP oppositing cdA
Summary for 6M7U
Entry DOI | 10.2210/pdb6m7u/pdb |
Descriptor | DNA polymerase eta, DNA (5'-D(*AP*GP*TP*GP*TP*GP*AP*G)-3'), DNA (5'-D(*AP*TP*(02I)P*CP*TP*CP*AP*CP*AP*CP*T)-3'), ... (8 entities in total) |
Functional Keywords | translesion synthesis, cda, dna binding protein, transferase-dna complex, transferase/dna |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 54999.17 |
Authors | |
Primary citation | Weng, P.J.,Gao, Y.,Gregory, M.T.,Wang, P.,Wang, Y.,Yang, W. Bypassing a 8,5'-cyclo-2'-deoxyadenosine lesion by human DNA polymerase eta at atomic resolution. Proc. Natl. Acad. Sci. U.S.A., 115:10660-10665, 2018 Cited by PubMed: 30275308DOI: 10.1073/pnas.1812856115 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.4 Å) |
Structure validation
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