6M5Q

A class C beta-lactamase mutant - Y150F

Summary for 6M5Q

• Entry DOI: 10.2210/pdb6m5q/pdb
• Descriptor: Beta-lactamase, (5R)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-3-[(2-{[(E)-iminomethyl]amino}ethyl)sulfanyl]-4,5-dihydro-1H-pyrrole-2-carbox ylic acid (3 entities in total)
• Functional Keywords: beta-lactamse, hydrolase
• Biological source: Klebsiella pneumoniae
• Total number of polymer chains: 1
• Total formula weight: 40998.68

Authors

Bae, D.W.,Jung, Y.E.,Cha, S.S. (deposition date: 2020-03-11, release date: 2021-01-20, Last modification date: 2023-11-29)

• Primary citation: Bae, D.W.,Jung, Y.E.,Jeong, B.G.,Cha, S.S.; Novel inhibition mechanism of carbapenems on the ACC-1 class C beta-lactamase.; Arch.Biochem.Biophys., 693:108570-108570, 2020; PubMed: 32888908; DOI: 10.1016/j.abb.2020.108570

Experimental method

X-RAY DIFFRACTION (1.3 Å)