6M1B

A new V27M variant of beta 2 microglobulin induced amyloidosis in a patient with long-term hemodialysis

Summary for 6M1B

• Entry DOI: 10.2210/pdb6m1b/pdb
• Descriptor: Beta-2-microglobulin, GLYCEROL, MAGNESIUM ION, ... (6 entities in total)
• Functional Keywords: beta 2 microglobulin, amyloidosis, hemodialysis, immune system
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 12254.96

Authors

So, M.,Nakahara, S.,Nakaniwa, T.,Tanaka, H.,Kurisu, G.,Goto, Y. (deposition date: 2020-02-25, release date: 2021-01-06, Last modification date: 2023-11-29)

• Primary citation: Mizuno, H.,Hoshino, J.,So, M.,Kogure, Y.,Fujii, T.,Ubara, Y.,Takaichi, K.,Nakaniwa, T.,Tanaka, H.,Kurisu, G.,Kametani, F.,Nakagawa, M.,Yoshinaga, T.,Sekijima, Y.,Higuchi, K.,Goto, Y.,Yazaki, M.; Dialysis-related amyloidosis associated with a novel beta 2 -microglobulin variant.; Amyloid, 28:42-49, 2021; PubMed: 32875920; DOI: 10.1080/13506129.2020.1813097

Experimental method

X-RAY DIFFRACTION (1.88 Å)