6M03

The crystal structure of COVID-19 main protease in apo form

Summary for 6M03

• Entry DOI: 10.2210/pdb6m03/pdb
• Descriptor: 3C-like proteinase (2 entities in total)
• Functional Keywords: coronavirus, covid-19, viral protease, biosynthetic protein
• Biological source: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)
• Total number of polymer chains: 1
• Total formula weight: 33825.55

Authors

Zhang, B.,Zhao, Y.,Jin, Z.,Liu, X.,Yang, H.,Rao, Z. (deposition date: 2020-02-19, release date: 2020-03-11, Last modification date: 2023-11-29)

• Primary citation: Zhao, Y.,Zhu, Y.,Liu, X.,Jin, Z.,Duan, Y.,Zhang, Q.,Wu, C.,Feng, L.,Du, X.,Zhao, J.,Shao, M.,Zhang, B.,Yang, X.,Wu, L.,Ji, X.,Guddat, L.W.,Yang, K.,Rao, Z.,Yang, H.; Structural basis for replicase polyprotein cleavage and substrate specificity of main protease from SARS-CoV-2.; Proc.Natl.Acad.Sci.USA, 119:e2117142119-e2117142119, 2022; PubMed: 35380892; DOI: 10.1073/pnas.2117142119

Experimental method

X-RAY DIFFRACTION (2 Å)