6M03

The crystal structure of COVID-19 main protease in apo form

6M03 の概要

• エントリーDOI: 10.2210/pdb6m03/pdb
• 分子名称: 3C-like proteinase (2 entities in total)
• 機能のキーワード: coronavirus, covid-19, viral protease, biosynthetic protein
• 由来する生物種: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 33825.55

構造登録者

Zhang, B.,Zhao, Y.,Jin, Z.,Liu, X.,Yang, H.,Rao, Z. (登録日: 2020-02-19, 公開日: 2020-03-11, 最終更新日: 2023-11-29)

• 主引用文献: Zhao, Y.,Zhu, Y.,Liu, X.,Jin, Z.,Duan, Y.,Zhang, Q.,Wu, C.,Feng, L.,Du, X.,Zhao, J.,Shao, M.,Zhang, B.,Yang, X.,Wu, L.,Ji, X.,Guddat, L.W.,Yang, K.,Rao, Z.,Yang, H.; Structural basis for replicase polyprotein cleavage and substrate specificity of main protease from SARS-CoV-2.; Proc.Natl.Acad.Sci.USA, 119:e2117142119-e2117142119, 2022; PubMed: 35380892; DOI: 10.1073/pnas.2117142119

実験手法

X-RAY DIFFRACTION (2 Å)