6LTR
Crystal structure of Cas12i2 ternary complex with single Mg2+ bound in catalytic pocket
Summary for 6LTR
Entry DOI | 10.2210/pdb6ltr/pdb |
Descriptor | Cas12i2, RNA (56-mer), DNA (5'-D(*GP*CP*CP*GP*CP*TP*TP*TP*CP*TP*TP*T)-3'), ... (8 entities in total) |
Functional Keywords | crispr-cas, cas12i2, cas12i2 ternary complex, hydrolase, hydrolase-rna-dna complex, hydrolase/rna/dna |
Biological source | unidentified More |
Total number of polymer chains | 5 |
Total formula weight | 155950.18 |
Authors | |
Primary citation | Huang, X.,Sun, W.,Cheng, Z.,Chen, M.,Li, X.,Wang, J.,Sheng, G.,Gong, W.,Wang, Y. Structural basis for two metal-ion catalysis of DNA cleavage by Cas12i2. Nat Commun, 11:5241-5241, 2020 Cited by PubMed: 33067443DOI: 10.1038/s41467-020-19072-6 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.51 Å) |
Structure validation
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