6LQA
voltage-gated sodium channel Nav1.5 with quinidine
Summary for 6LQA
Entry DOI | 10.2210/pdb6lqa/pdb |
EMDB information | 0942 |
Descriptor | Sodium channel protein type 5 subunit alpha, 2-acetamido-2-deoxy-beta-D-glucopyranose, Quinidine (3 entities in total) |
Functional Keywords | membrane protein, voltage-gated sodium channel, transport protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 234059.23 |
Authors | |
Primary citation | Li, Z.,Jin, X.,Wu, T.,Huang, G.,Wu, K.,Lei, J.,Pan, X.,Yan, N. Structural Basis for Pore Blockade of the Human Cardiac Sodium Channel Na v 1.5 by the Antiarrhythmic Drug Quinidine*. Angew.Chem.Int.Ed.Engl., 60:11474-11480, 2021 Cited by PubMed: 33684260DOI: 10.1002/anie.202102196 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.3 Å) |
Structure validation
Download full validation report