6LPQ

Crystal structure of human D-2-hydroxyglutarate dehydrogenase in complex with D-malate (D-MAL)

6LPQ の概要

• エントリーDOI: 10.2210/pdb6lpq/pdb
• 分子名称: D-2-hydroxyglutarate dehydrogenase, mitochondrial, FLAVIN-ADENINE DINUCLEOTIDE, ZINC ION, ... (4 entities in total)
• 機能のキーワード: dehydrogenase, flavoprotein, oxidoreductase
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 106635.84

構造登録者

Yang, J.,Zhu, H.,Ding, J. (登録日: 2020-01-12, 公開日: 2021-01-13, 最終更新日: 2023-11-29)

• 主引用文献: Yang, J.,Zhu, H.,Zhang, T.,Ding, J.; Structure, substrate specificity, and catalytic mechanism of human D-2-HGDH and insights into pathogenicity of disease-associated mutations.; Cell Discov, 7:3-3, 2021; PubMed: 33431826; DOI: 10.1038/s41421-020-00227-0

実験手法

X-RAY DIFFRACTION (2.8 Å)