6LNN

Crystal structure of MERS-CoV N-NTD complexed with ligand P4-1

Summary for 6LNN

• Entry DOI: 10.2210/pdb6lnn/pdb
• Descriptor: Nucleoprotein, 5-propoxy-1H-indole (3 entities in total)
• Functional Keywords: middle east respiratory syndrome coronavirus, nucleocapsid protein, n-terminal domain, viral protein
• Biological source: Middle East respiratory syndrome-related coronavirus
• Total number of polymer chains: 4
• Total formula weight: 57262.53

Authors

Hou, M.H.,Lin, S.M.,Hsu, J.N. (deposition date: 2019-12-31, release date: 2021-01-13, Last modification date: 2023-11-29)

• Primary citation: Hsu, J.N.,Chen, J.S.,Lin, S.M.,Hong, J.Y.,Chen, Y.J.,Jeng, U.S.,Luo, S.Y.,Hou, M.H.; Targeting the N-Terminus Domain of the Coronavirus Nucleocapsid Protein Induces Abnormal Oligomerization via Allosteric Modulation.; Front Mol Biosci, 9:871499-871499, 2022; PubMed: 35517857; DOI: 10.3389/fmolb.2022.871499

Experimental method

X-RAY DIFFRACTION (2.634 Å)