6LG7
Crystal Structure of the first bromodomain of human BRD4 in complex with compound BDF-2030
Summary for 6LG7
Entry DOI | 10.2210/pdb6lg7/pdb |
Descriptor | Bromodomain-containing protein 4, 2-azanyl-6-fluoranyl-4-imidazol-1-yl-quinolin-8-ol (3 entities in total) |
Functional Keywords | brd4, inhibitor, complex, dna binding protein, transcription |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 15127.41 |
Authors | |
Primary citation | Xu, H.,Zuo, Y. Lead-Opt: An efficient tool for structural optimization of lead compounds To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.83 Å) |
Structure validation
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