6L69

Crystal structure of CYP154C2 from Streptomyces avermitilis

Summary for 6L69

Entry DOI	10.2210/pdb6l69/pdb
Descriptor	Cytochrome P450 hydroxylase, PROTOPORPHYRIN IX CONTAINING FE (3 entities in total)
Functional Keywords	cytochrome p450, substrate-free, hydroxylase, oxidoreductase
Biological source	Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680)
Total number of polymer chains	2
Total formula weight	91777.80
Authors	Xu, L.H.,Fushinobu, S. (deposition date: 2019-10-28, release date: 2020-09-23, Last modification date: 2023-11-22)
Primary citation	Wang, Q.,Ma, B.,Fushinobu, S.,Zhang, C.,Xu, L.H. Regio- and stereoselective hydroxylation of testosterone by a novel cytochrome P450 154C2 from Streptomyces avermitilis. Biochem.Biophys.Res.Commun., 522:355-361, 2020 Cited by PubMed: 31767148 DOI: 10.1016/j.bbrc.2019.11.091 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.5 Å)

Structure validation