6L3M

Crystal Structure of the acyltransferase domain from the third module of the ansamitocin polyketide synthase

Summary for 6L3M

• Entry DOI: 10.2210/pdb6l3m/pdb
• Descriptor: Polyketide synthase, GLYCEROL, 2-methoxypropanedioic acid, ... (5 entities in total)
• Functional Keywords: polyketide, acyltransferase, acp-linked extender unit, carrier specificity, biosynthesis, transferase
• Biological source: Actinosynnema pretiosum subsp. auranticum
• Total number of polymer chains: 4
• Total formula weight: 178136.52

Authors

Zhang, F.,Zheng, J. (deposition date: 2019-10-11, release date: 2019-12-18, Last modification date: 2023-11-22)

• Primary citation: Zhang, F.,Ji, H.,Ali, I.,Deng, Z.,Bai, L.,Zheng, J.; Structural and Biochemical Insight into the Recruitment of Acyl Carrier Protein-Linked Extender Units in Ansamitocin Biosynthesis.; Chembiochem, 21:1309-1314, 2020; PubMed: 31777147; DOI: 10.1002/cbic.201900628

Experimental method

X-RAY DIFFRACTION (1.77 Å)