6L0A

Crystal structure of dihydroorotase in complex with malate at pH7 from Saccharomyces cerevisiae

Summary for 6L0A

• Entry DOI: 10.2210/pdb6l0a/pdb
• Descriptor: Dihydroorotase, ZINC ION, (2S)-2-hydroxybutanedioic acid, ... (4 entities in total)
• Functional Keywords: dihydropyrimidinase dihydroorotase metalloenzyme, hydrolase
• Biological source: Saccharomyces cerevisiae S288C (Baker's yeast)
• Total number of polymer chains: 4
• Total formula weight: 166973.04

Authors

Guan, H.H.,Huang, Y.H.,Huang, C.Y.,Chen, C.J. (deposition date: 2019-09-26, release date: 2020-12-02, Last modification date: 2021-12-15)

• Primary citation: Guan, H.H.,Huang, Y.H.,Lin, E.S.,Chen, C.J.,Huang, C.Y.; Structural Analysis of Saccharomyces cerevisiae Dihydroorotase Reveals Molecular Insights into the Tetramerization Mechanism; Molecules, 2021; DOI: 10.3390/molecules26237249

Experimental method

X-RAY DIFFRACTION (1.79 Å)