6KOG
Ketosynthase domain in tenuazonic acid synthetase 1 (TAS1).
Summary for 6KOG
Entry DOI | 10.2210/pdb6kog/pdb |
Descriptor | Hybrid PKS-NRPS synthetase TAS1, GLYCEROL, SULFATE ION, ... (4 entities in total) |
Functional Keywords | ketosynthase domain, cyclization, tetramic acid ring formation, nrps-pks hybrid enzyme, toxin, biosynthetic protein |
Biological source | Pyricularia oryzae 70-15 (Rice blast fungus) |
Total number of polymer chains | 2 |
Total formula weight | 96223.37 |
Authors | Yun, C.S.,Nishimoto, K.,Motoyama, T.,Hino, T.,Nagano, S.,Osada, H. (deposition date: 2019-08-10, release date: 2020-07-01, Last modification date: 2023-11-22) |
Primary citation | Yun, C.S.,Nishimoto, K.,Motoyama, T.,Shimizu, T.,Hino, T.,Dohmae, N.,Nagano, S.,Osada, H. Unique features of the ketosynthase domain in a nonribosomal peptide synthetase-polyketide synthase hybrid enzyme, tenuazonic acid synthetase 1. J.Biol.Chem., 295:11602-11612, 2020 Cited by PubMed: 32565425DOI: 10.1074/jbc.RA120.013105 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.68 Å) |
Structure validation
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