6KN4
HUMAN PARALLEL STRANDED 7-MER G-QUADRUPLEX COMPLEXED WITH 2 ADRIAMYCIN (DM2) MOLECULES
Summary for 6KN4
Entry DOI | 10.2210/pdb6kn4/pdb |
Descriptor | DNA (5'-D(*TP*TP*AP*GP*GP*GP*T)-3'), DOXORUBICIN (2 entities in total) |
Functional Keywords | g-quadruplex, adriamycin, doxorubicin, dna |
Biological source | Homo sapiens |
Total number of polymer chains | 4 |
Total formula weight | 9760.82 |
Authors | Barthwal, R.,Raje, S.,Pandav, K. (deposition date: 2019-08-03, release date: 2020-03-18, Last modification date: 2024-05-01) |
Primary citation | Barthwal, R.,Raje, S.,Pandav, K. Structural basis for stabilization of human telomeric G-quadruplex [d-(TTAGGGT)] 4 by anticancer drug adriamycin. J.Biomol.Struct.Dyn., 39:795-815, 2021 Cited by PubMed: 32070245DOI: 10.1080/07391102.2020.1730969 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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