6KN4

HUMAN PARALLEL STRANDED 7-MER G-QUADRUPLEX COMPLEXED WITH 2 ADRIAMYCIN (DM2) MOLECULES

Summary for 6KN4

• Entry DOI: 10.2210/pdb6kn4/pdb
• Descriptor: DNA (5'-D(*TP*TP*AP*GP*GP*GP*T)-3'), DOXORUBICIN (2 entities in total)
• Functional Keywords: g-quadruplex, adriamycin, doxorubicin, dna
• Biological source: Homo sapiens
• Total number of polymer chains: 4
• Total formula weight: 9760.82

Authors

Barthwal, R.,Raje, S.,Pandav, K. (deposition date: 2019-08-03, release date: 2020-03-18, Last modification date: 2024-05-01)

• Primary citation: Barthwal, R.,Raje, S.,Pandav, K.; Structural basis for stabilization of human telomeric G-quadruplex [d-(TTAGGGT)] 4 by anticancer drug adriamycin.; J.Biomol.Struct.Dyn., 39:795-815, 2021; PubMed: 32070245; DOI: 10.1080/07391102.2020.1730969

Experimental method

SOLUTION NMR