6KJQ

Functional and structural insights into the unusual oxyanion hole-like geometry in macrolactin acyltransferase selective for dicarboxylic acyl donors

6KJQ の概要

• エントリーDOI: 10.2210/pdb6kjq/pdb
• 分子名称: Putative beta-lactamase, (3~{Z},5~{E},8~{S},9~{E},11~{E},14~{S},16~{R},17~{Z},19~{E},24~{R})-24-methyl-8,14,16-tris(oxidanyl)-1-oxacyclotetracosa-3,5,9,11,17,19-hexaen-2-one (3 entities in total)
• 機能のキーワード: acyltransferase, transferase
• 由来する生物種: Jeotgalibacillus marinus
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 44567.85

構造登録者

Xiao, F.,Dong, S.,Feng, Y.,Li, W. (登録日: 2019-07-23, 公開日: 2020-07-29, 最終更新日: 2023-11-22)

• 主引用文献: Xiao, F.,Dong, S.,Liu, Y.,Feng, Y.,Li, H.,Yun, C.H.,Cui, Q.,Li, W.; Structural Basis of Specificity for Carboxyl-Terminated Acyl Donors in a Bacterial Acyltransferase.; J.Am.Chem.Soc., 142:16031-16038, 2020; PubMed: 32803979; DOI: 10.1021/jacs.0c07331

実験手法

X-RAY DIFFRACTION (2.35 Å)