6KGH

Crystal structure of Penicillin binding protein 3 (PBP3) from Mycobacterium tuerculosis (apo-form)

Summary for 6KGH

Entry DOI	10.2210/pdb6kgh/pdb
Descriptor	Penicillin-binding protein PbpB, COBALT (II) ION, SODIUM ION, ... (4 entities in total)
Functional Keywords	penicillin-binding protein, native form, mycobacterium tuberculosis, transferase
Biological source	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Total number of polymer chains	1
Total formula weight	60000.80
Authors	Lu, Z.K.,Zhang, A.L.,Liu, X.,Guddat, L.,Yang, H.T.,Rao, Z.H. (deposition date: 2019-07-11, release date: 2020-03-11)
Primary citation	Lu, Z.,Wang, H.,Zhang, A.,Liu, X.,Zhou, W.,Yang, C.,Guddat, L.,Yang, H.,Schofield, C.J.,Rao, Z. Structures ofMycobacterium tuberculosisPenicillin-Binding Protein 3 in Complex with Fivebeta-Lactam Antibiotics Reveal Mechanism of Inactivation. Mol.Pharmacol., 97:287-294, 2020 Cited by PubMed: 32086254 DOI: 10.1124/mol.119.118042 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.108 Å)

Structure validation