6KGH

Crystal structure of Penicillin binding protein 3 (PBP3) from Mycobacterium tuerculosis (apo-form)

6KGH の概要

• エントリーDOI: 10.2210/pdb6kgh/pdb
• 分子名称: Penicillin-binding protein PbpB, COBALT (II) ION, SODIUM ION, ... (4 entities in total)
• 機能のキーワード: penicillin-binding protein, native form, mycobacterium tuberculosis, transferase
• 由来する生物種: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 60000.80

構造登録者

Lu, Z.K.,Zhang, A.L.,Liu, X.,Guddat, L.,Yang, H.T.,Rao, Z.H. (登録日: 2019-07-11, 公開日: 2020-03-11)

• 主引用文献: Lu, Z.,Wang, H.,Zhang, A.,Liu, X.,Zhou, W.,Yang, C.,Guddat, L.,Yang, H.,Schofield, C.J.,Rao, Z.; Structures ofMycobacterium tuberculosisPenicillin-Binding Protein 3 in Complex with Fivebeta-Lactam Antibiotics Reveal Mechanism of Inactivation.; Mol.Pharmacol., 97:287-294, 2020; PubMed: 32086254; DOI: 10.1124/mol.119.118042

実験手法

X-RAY DIFFRACTION (2.108 Å)