6KDF

Crystal structure of the alpha beta heterodimer of human IDH3 in APO form.

Summary for 6KDF

Entry DOI	10.2210/pdb6kdf/pdb
Descriptor	Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial, Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial (2 entities in total)
Functional Keywords	nad dependent isocitrate dehydrogenase, oxidoreductase
Biological source	Homo sapiens (Human) More
Total number of polymer chains	16
Total formula weight	612239.75
Authors	Sun, P.,Ding, J. (deposition date: 2019-07-02, release date: 2019-09-25, Last modification date: 2023-11-22)
Primary citation	Sun, P.,Ma, T.,Zhang, T.,Zhu, H.,Zhang, J.,Liu, Y.,Ding, J. Molecular basis for the function of the alpha beta heterodimer of human NAD-dependent isocitrate dehydrogenase. J.Biol.Chem., 294:16214-16227, 2019 Cited by PubMed: 31515270 DOI: 10.1074/jbc.RA119.010099 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.05 Å)

Structure validation