6KD5

Crystal structure of the extracellular domain of MSPL/TMPRSS13 in complex with dec-RVKR-cmk inhibitor

Summary for 6KD5

Entry DOI	10.2210/pdb6kd5/pdb
Descriptor	Transmembrane protease serine 13, DECANOYL-ARG-VAL-LYS-ARG-CHLOROMETHYLKETONE INHIBITOR, alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
Functional Keywords	hydrolase, structural protein-inhibitor complex, structural protein/inhibitor
Biological source	Homo sapiens (Human) More
Total number of polymer chains	3
Total formula weight	49190.20
Authors	Ohno, A.,Maita, N.,Okumura, Y.,Nikawa, T. (deposition date: 2019-06-30, release date: 2020-06-24, Last modification date: 2023-11-22)
Primary citation	Ohno, A.,Maita, N.,Tabata, T.,Nagano, H.,Arita, K.,Ariyoshi, M.,Uchida, T.,Nakao, R.,Ulla, A.,Sugiura, K.,Kishimoto, K.,Teshima-Kondo, S.,Okumura, Y.,Nikawa, T. Crystal structure of inhibitor-bound human MSPL that can activate high pathogenic avian influenza. Life Sci Alliance, 4:-, 2021 Cited by PubMed: 33820827 DOI: 10.26508/lsa.202000849 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.6 Å)

Structure validation