6KAY
X-ray structure of human PPARalpha ligand binding domain-GW7647 co-crystals obtained by soaking
Summary for 6KAY
Entry DOI | 10.2210/pdb6kay/pdb |
Descriptor | Peroxisome proliferator-activated receptor alpha, 2-[(4-{2-[(4-cyclohexylbutyl)(cyclohexylcarbamoyl)amino]ethyl}phenyl)sulfanyl]-2-methylpropanoic acid, GLYCEROL, ... (4 entities in total) |
Functional Keywords | nuclear receptor, protein-ligand complex, ppar, transcription |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 31450.90 |
Authors | Kamata, S.,Suda, K.,Saito, K.,Oyama, T.,Ishii, I. (deposition date: 2019-06-24, release date: 2020-11-11, Last modification date: 2023-11-22) |
Primary citation | Kamata, S.,Oyama, T.,Saito, K.,Honda, A.,Yamamoto, Y.,Suda, K.,Ishikawa, R.,Itoh, T.,Watanabe, Y.,Shibata, T.,Uchida, K.,Suematsu, M.,Ishii, I. PPAR alpha Ligand-Binding Domain Structures with Endogenous Fatty Acids and Fibrates. Iscience, 23:101727-101727, 2020 Cited by PubMed: 33205029DOI: 10.1016/j.isci.2020.101727 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.735 Å) |
Structure validation
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