6JZ8
b-glucuronidase from Ruminococcus gnavus in complex with D-glucaro 1,5-lactone
Summary for 6JZ8
| Entry DOI | 10.2210/pdb6jz8/pdb |
| Descriptor | Beta-glucuronidase, (2S,3S,4S,5R)-3,4,5-trihydroxy-6-oxo-oxane-2-carboxylic acid (3 entities in total) |
| Functional Keywords | b-glucuronidase, hydrolase |
| Biological source | [Ruminococcus] gnavus |
| Total number of polymer chains | 2 |
| Total formula weight | 140462.01 |
| Authors | Dashnyam, P.,Lin, H.Y. (deposition date: 2019-04-30, release date: 2020-06-10, Last modification date: 2023-11-22) |
| Primary citation | Dashnyam, P.,Lin, H.Y.,Chen, C.Y.,Gao, S.,Yeh, L.F.,Hsieh, W.C.,Tu, Z.,Lin, C.H. Substituent Position of Iminocyclitols Determines the Potency and Selectivity for Gut Microbial Xenobiotic-Reactivating Enzymes. J.Med.Chem., 63:4617-4627, 2020 Cited by PubMed: 32105467DOI: 10.1021/acs.jmedchem.9b01918 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.583 Å) |
Structure validation
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