6JSD

Crystal structure of the domain-swapped dimer H434A variant of the C-terminal domain of HtaA from Corynebacterium glutamicum

6JSD の概要

• エントリーDOI: 10.2210/pdb6jsd/pdb
• 分子名称: Hypothetical membrane protein, ISOPROPYL ALCOHOL (3 entities in total)
• 機能のキーワード: heme, heme transport, heme-binding protein
• 由来する生物種: Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 36383.25

構造登録者

Muraki, N.,Aono, S. (登録日: 2019-04-08, 公開日: 2019-11-20, 最終更新日: 2023-11-22)

主引用文献

Muraki, N.,Kitatsuji, C.,Okamoto, Y.,Uchida, T.,Ishimori, K.,Aono, S.
Structural basis for the heme transfer reaction in heme uptake machinery from Corynebacteria.
Chem.Commun.(Camb.), 55:13864-13867, 2019

PubMed Abstract: The crystal structures of the conserved region domains of HtaA and HtaB, which act as heme binding/transport proteins in the heme uptake machinery in Corynebacterium glutamicum, are determined for the first time. The molecular mechanism of heme transfer among these proteins is proposed based on the spectroscopic and structural analyses.

PubMed: 31670736
DOI: 10.1039/c9cc07369h

実験手法

X-RAY DIFFRACTION (2.042 Å)