6JR4
Crystal structure of a NIR-emitting DNA-stabilized Ag16 nanocluster
Summary for 6JR4
| Entry DOI | 10.2210/pdb6jr4/pdb |
| Descriptor | DNA (5'-D(*CP*AP*CP*CP*TP*AP*GP*CP*GP*A)-3'), SILVER ION, CALCIUM ION, ... (4 entities in total) |
| Functional Keywords | nanocluster, silver, dna |
| Biological source | synthetic construct |
| Total number of polymer chains | 4 |
| Total formula weight | 16235.12 |
| Authors | Kondo, J.,Cerretani, C.,Kanazawa, H.,Vosch, T. (deposition date: 2019-04-02, release date: 2019-08-28, Last modification date: 2024-03-27) |
| Primary citation | Cerretani, C.,Kanazawa, H.,Vosch, T.,Kondo, J. Crystal structure of a NIR-Emitting DNA-Stabilized Ag16Nanocluster. Angew.Chem.Int.Ed.Engl., 58:17153-17157, 2019 Cited by PubMed Abstract: DNA has been used as a scaffold to stabilize small, atomically monodisperse silver nanoclusters, which have attracted attention due to their intriguing photophysical properties. Herein, we describe the X-ray crystal structure of a DNA-encapsulated, near-infrared emitting Ag nanocluster (DNA-Ag NC). The asymmetric unit of the crystal contains two DNA-Ag NCs and the crystal packing between the DNA-Ag NCs is promoted by several interactions, such as two silver-mediated base pairs between 3'-terminal adenines, two phosphate-Ca -phosphate interactions, and π-stacking between two neighboring thymines. Each Ag NC is confined by two DNA decamers that take on a horse-shoe-like conformation and is almost fully shielded from the solvent environment. This structural insight will aid in the determination of the structure/photophysical property relationship for this class of emitters and opens up new research opportunities in fluorescence imaging and sensing using noble-metal clusters. PubMed: 31411360DOI: 10.1002/anie.201906766 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.798 Å) |
Structure validation
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