6JP9

Crsytal structure of a XMP complexed ATPPase subunit of M. jannaschii GMP synthetase

6JP9 の概要

• エントリーDOI: 10.2210/pdb6jp9/pdb
• 分子名称: GMP synthase [glutamine-hydrolyzing] subunit B, XANTHOSINE-5'-MONOPHOSPHATE, TRIETHYLENE GLYCOL, ... (5 entities in total)
• 機能のキーワード: purine biosynthesis, methanocaldococcus jannaschii, gmp synthetase, atp pyrophosphatase, p-loop, ligase
• 由来する生物種: Methanocaldococcus jannaschii DSM 2661 (Methanococcus jannaschii)
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 141140.38

構造登録者

Shivakumarasamy, S.,Balaram, H. (登録日: 2019-03-26, 公開日: 2020-04-22, 最終更新日: 2023-11-29)

• 主引用文献: Shivakumaraswamy, S.,Kumar, S.,Bellur, A.,Polisetty, S.D.,Balaram, H.; Mechanistic Insights into the Functioning of a Two-Subunit GMP Synthetase, an Allosterically Regulated, Ammonia Channeling Enzyme.; Biochemistry, 61:1988-2006, 2022; PubMed: 36040251; DOI: 10.1021/acs.biochem.2c00151

実験手法

X-RAY DIFFRACTION (2.1 Å)