Crystal structure of pyrrolysyl-tRNA synthetase from Methanomethylophilus alvus

Summary for 6JP2

DescriptorPyrrolysyl-tRNA synthetase (2 entities in total)
Functional Keywordsaminoacyl-trna synthetase, trna, pyrrolysyl-trna synthetase, non-natural amino acids, translation, ligase
Biological sourceCandidatus Methanomethylophilus alvus
Total number of polymer chains4
Total molecular weight124513.47
Yanagisawa, T.,Kuratani, M.,Yokoyama, S. (deposition date: 2019-03-25, release date: 2019-05-22, Last modification date: 2020-04-29)
Primary citation
Seki, E.,Yanagisawa, T.,Kuratani, M.,Sakamoto, K.,Yokoyama, S.
Fully Productive Cell-Free Genetic Code Expansion by Structure-Based Engineering ofMethanomethylophilus alvusPyrrolysyl-tRNA Synthetase.
Acs Synth Biol, 9:718-732, 2020
PubMed: 32182048 (PDB entries with the same primary citation)
DOI: 10.1021/acssynbio.9b00288
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.2577 0.6% 1.9% 6.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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