6JKW

Seleno-methionine PNGM-1 from deep-sea sediment metagenome

6JKW の概要

• エントリーDOI: 10.2210/pdb6jkw/pdb
• 分子名称: Metallo-beta-lactamases PNGM-1, ZINC ION (3 entities in total)
• 機能のキーワード: mbls, zinc binding motif, antibiotic resistance, metagenome, structural genomics, psi-biology, transferase
• 由来する生物種: Acinetobacter baumannii
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 341036.36

構造登録者

Hong, M.K.,Park, K.S.,Jeon, J.H.,Lee, J.H.,Park, Y.S.,Lee, S.H.,Kang, L.W. (登録日: 2019-03-02, 公開日: 2019-04-17, 最終更新日: 2024-11-13)

主引用文献

Kang, L.W.,Lee, S.H.
PNGM 1 a novel subclass B3 metallo beta lactamase from a deep sea sediment metagenome
Journal of Global Antimicrobial Resistance, 14:302-305, 2018

PubMed Abstract: In order to find antimicrobial resistance gene(s) pre-dating the use of antibiotics through metagenomics, functional screening of a metagenomic library from the deep-seep sediments of Edison Seamount (ca. 10000 years old) was performed.

PubMed: 29842976
DOI: 10.1016/j.jgar.2018.05.021.

実験手法

X-RAY DIFFRACTION (2.29 Å)