6JKT

Crystal structure of aspartate transcarbamoylase from Trypanosoma cruzi in complex with N-(PHOSPHONACETYL)-L-ASPARTIC ACID (PALA).

Summary for 6JKT

• Entry DOI: 10.2210/pdb6jkt/pdb
• Descriptor: Aspartate carbamoyltransferase, N-(PHOSPHONACETYL)-L-ASPARTIC ACID, GLYCEROL, ... (4 entities in total)
• Functional Keywords: atcase, pyrimidine metabolism, transferase
• Biological source: Trypanosoma cruzi
• Total number of polymer chains: 6
• Total formula weight: 218916.20

Authors

Matoba, K.,Shiba, T.,Nara, T.,Aoki, T.,Nagasaki, S.,Hayamizu, R.,Honma, T.,Tanaka, A.,Inoue, M.,Matsuoka, S.,Balogun, E.O.,Inaoka, D.K.,Kita, K.,Harada, S. (deposition date: 2019-03-01, release date: 2020-03-04, Last modification date: 2023-11-22)

• Primary citation: Matoba, K.,Shiba, T.,Nara, T.,Aoki, T.,Nagasaki, S.,Hayamizu, R.,Honma, T.,Tanaka, A.,Inoue, M.,Matsuoka, S.,Balogun, E.O.,Inaoka, D.K.,Kita, K.,Harada, S.; Crystallographic snapshots of Trypanosoma cruzi aspartate transcarbamoylase revealed an ordered Bi-Bi reaction mechanism; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.3 Å)