6JKM

Crystal structure of BubR1 kinase domain

6JKM の概要

• エントリーDOI: 10.2210/pdb6jkm/pdb
• 分子名称: Mitotic checkpoint control protein kinase BUB1, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... (5 entities in total)
• 機能のキーワード: kinase, mitotic checkpoint, transferase
• 由来する生物種: Drosophila melanogaster (Fruit fly)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 40171.76

構造登録者

Lin, L.,Ye, S.,Huang, Y.,Liu, X.,Zhang, R.,Yao, X. (登録日: 2019-03-01, 公開日: 2019-06-26, 最終更新日: 2023-11-22)

• 主引用文献: Huang, Y.,Lin, L.,Liu, X.,Ye, S.,Yao, P.Y.,Wang, W.,Yang, F.,Gao, X.,Li, J.,Zhang, Y.,Zhang, J.,Yang, Z.,Liu, X.,Yang, Z.,Zang, J.,Teng, M.,Wang, Z.,Ruan, K.,Ding, X.,Li, L.,Cleveland, D.W.,Zhang, R.,Yao, X.; BubR1 phosphorylates CENP-E as a switch enabling the transition from lateral association to end-on capture of spindle microtubules.; Cell Res., 29:562-578, 2019; PubMed: 31201382; DOI: 10.1038/s41422-019-0178-z

実験手法

X-RAY DIFFRACTION (1.95 Å)